CRATER will be back! The second edition will take place on 15-17 October 2025 in Warsaw (Poland)

Conference programme

Day 1 – 7 September

  • 8:00

    Registration & Coffee & Cookies

  • 9:00

    Opening remarks

  • 9:20

    ICTER - research centre with a mission to save sight

    Maciej Wojtkowski
  • 9:40

    Service Appreciation Ceremony

    Chris Dainty
  • 9:50

    Plenary: The special barrier functions of the retinal pigment epithelium, a target for disease monitoring

    Olaf Strauss
  • 10:30

    Coffee break

  • 10:50

    Plenary: Visual restauration in blind patients: from prosthesis to sonogenetic therapy

    Serge Picaud
  • 11:30

    Plenary: Cellular Senescence in Retinal Vascular Diseases

    Przemysław Sapieha
  • 12:10

    Plenary: Documenting the spatial redistribution of hyperpigmented spots during enlargment of geographic atrophy

    Michel Paques
  • 12:50

    Lunch break

  • 14:00

    Parallel session I.1: Wavefront control and two photons in the eye

    Chaired by Ryszard Naskręcki, Auditorium A
    • Invited: Developing two-photon excited fluorescence imaging to assess retinal function
    • Invited: Clinical Applications of AOSLO Retinal Imagin
    • In vivo imaging of the human eye using a two-pho- ton-excited fluorescence scanning laser ophthal- moscope
    • Invited: Peripheral optics in the eye: from myopia to cataracts
    • Spectral sensitivity curve for two-photon vision
  • 14:00

    Parallel session I.2: From gene to eye treatment

    Chaired by Wiesław Gruszecki, Auditorium B
    • Invited: Modelling inherited retinal diseases with retinal organoids
    • Visual information processing in retinal degeneration and vision restoration
    • Embryonic knockout of Nr2e3 protects photore- ceptors in three different mouse models of retinal degeneration
      Alexander Kolesnikov
    • Invited: Rhodopsin confromational modulators and their potential use in the treatment of retinitis pigmentosa
    • Multimodal approaches for resolving dynamical bio- logical processes by single-cell sequencing
  • 16:00

    Poster session

    • P1: A mechanical model of the human eye to investigate the effect of intraocular pressure on lens displacement
      Magdalena Asejczyk
    • P2: Shedding light on calcium dynamics and membrane potential control with optogenetics
      Bartłomiej Bałamut
    • P3: Supramolecular complexes of GCAP1 in inherited retinal dystrophies
      Amedeo Biasi
    • P4: From bicelles to a model bilayer containing rhodopsin – a novel method for biomimetic studies
      Justyna Bożek & Patryk Bielski
    • P5: A biophysical computational model of a cortical column in the primary visual cortex
      Mehdi Borjkhani
    • P6: Mapping the structure and function of whole-mount retinal organoids
      Marina Cunquero
    • P7: Two-photon excited fluorescence scanning laser ophthalmoscope enables robust retina imaging in healthy volunteers
      Michał Dąbrowski
    • P8: The comparison between software optimized accommodation and formula given accommodation
      Fabian Dębowy
    • P9: 4-D Imaging of Vitreous Using SS-OCT System
      Evangeline Priyadharshini Devaraj
    • P10: Two genetic mouse models of Stargardt disease display differences in targeting of ceramide levels and immune cell crosstalk in response to retinal degeneration
      Zachary Engfer
    • P11: Endoscopic en-face optical coherence tomography and fluorescence imaging using correlation-based probe tracking
      Adrian Fernandez Uceda
    • P12: Hyperspectral detection in multiphoton microscopy without a spectrometer
      Paulina Frycie
    • P13: Creation of viral plasmids for enhancement of the signal transduction in the retina
      Anna Galińska
    • P14: Optical coherence tomography-based tear clearance rate as a marker of dry eye disease
      Izabela Garaszczuk
    • P15: Structure and conformational changes of RBP3
      Luca Gessa
    • P16: Asynchronous Kalman filtering for real time needle position estimation in OCT-assisted surgery
      Krzysztof Gromada
    • P17: Assessment of corneal dynamics in normal, forme fruste and keratoconic eyes using air-puff OCT-based optical biometer
      Ireneusz Grulkowski
    • P18: Contrast sensitivity function for two-photon vision based on the method of determining the luminance of the stimuli
      Oliwia Kaczkoś
    • P19: Subclinical Keratoconus Detection using Deep Learning on Raw Anterior-Segment Optical Coherence Tomography Imaging
      Lynn Kandakji
    • P20: Robotic arm-based surgical tool tracking for real-time display of intraoperative OCT cross-sections at the surgical tool tip
    • P21: Optimization-free, phase utilizing alignment method for multiple spectrometer-based OCT
      Piotr Kasprzycki
    • P22: A protein structural biology approach to understanding morphological changes in photoreceptor outer segment after light activation: a closer look at PDE6
      Vineeta Kaushik & Łukasz Olejnik
    • P23: Wide dynamic range digital aberrometry and fast anterior-segment imaging with MHz SS-OCT
      Mengyuan Ke
    • P24: Multi-range scanning laser ophthalmoscope for imaging the morphology and dynamics of the retinal vessels
      Julia Kochańska
    • P25: Phase analysis of retinal image sequences using Fourier transformation
      Radim Kolar
    • P26: Current impulses induce different activity patterns in the visual system
      Katarzyna Kordecka
    • P27: Deep Learning models for retinal cell classification
      Maciej Kostałkowski
    • P28: Heterochromatic flicker photometry for two-photon vision
      Agata Kotulska
    • P29: Hemodynamics monitoring in mouse retinal vessels via ultrafast volumetric Spatio-Temporal Optical Coherence Tomography (STOC-T) imaging
      Wiktor Kulesza
    • P30: Regulation of Retinal membrane Guanylate Cyclases (RetGC’s) by modulator proteins
      Nelam Kumar & Sathi Goswani
    • P31: Compact, linearly polarized, high-brightness supercontinuum source for biomedical applications
      Katarzyna Kunio
    • P32: Developing a digital-twin of human retina enabling simulation of OCT image formation
      En Lu
    • P33: Effect of laser pulse train parameters on the brightness of a two-photon stimulus
      Marcin Marzejon
    • P34: Investigation of the relation between eye refractive error and air-puff induced corneal dynamics measured with optical coherence tomography
      Ewa Mączyńska-Walkowiak
    • P35: Infrared pupillometry: a neurological tool for evaluating therapeutics for inherited retinal disorders
      Carolline Menezes
    • P36: Refining the STOC-T system for in vivo cellular-level imaging of the human retina
      Marta Mikuła-Zdańkowska, Piotr Węgrzyn
    • P37: Opto-mechanical design of multi-spot air-puff OCT clinical prototype
      Jadwiga Milkiewicz
    • P38: Lactate Receptor, HCAR1 Deficiency Leads to Cellular Stress Compromising Choroidal Integrity of the Developing Outer Retina
      Monir Modaresinejad
    • P39: Signal transduction cascade modulation using TRP protein
      Milena Mućka
    • P40: Using dynamic light scattering enhances the imaging capabilities of optical coherence tomography
      Klaudia Nowacka
    • P41: Working memory items outside the focus of attention: evidence from single-neuron recordings in humans.
      Katarzyna Paluch
    • P42: Recombinant Rhodopsin, a novel optogenetic tool
      Jagoda Płaczkiewicz
    • P43: Non-destructive characterization and classification of choroidal melanoma biopsies with Raman Spectroscopy
      José Javier Ruiz
    • P44: Stable cell line generation for Rabies VLPs production
      Karolina Saran
    • P45: Optical signal discontinuity zones of the crystalline lens at different accommodation demands
      Keerthana Soman
    • P46: Widely tunable femtosecond fiber laser (870-1085 nm) with adjustable repetition rate for studying two-photon vision
      Dorota Stachowiak
    • P47: MOEMS endomicroscopy probe with Mirau micro-interferometer and 2-axis electrothermal micro-scanner for OCT imaging using Lissajous trajectory scanning
      Przemysław Struk
    • P48: Lensless digital holographic microscopy: numerical and experimental advancements
      Maciej Trusiak
    • P49: Volumetric Image Registration Algorithm for Phase-Based Functional Optoretinography in Fourier-Domain Full-Field OCT
      Maciej Wielgo
    • P50: In the world of preservative-free eye drops
      Jakub Zarczuk
    • P51: Common path quantitative phase microscopy and tomography: new solutions and applications
      Piotr Zdańkowski
  • 18:30

    Conference reception

    • Closing at 22:00

Day 2 – 8 September

  • 8:00

    Registration & Coffee & Cookies

  • 8:30

    Parallel session II.1 – New imaging methods for anterior eye

    Chaired by Bartłomiej Kałużny, Auditorium A
    • New insights into development of aging of the cry- stalline lens from high-resolution and high-sensitive in vivo optical imaging
      Ireneusz Grulkowski
    • Cornea ultra-fast confocal and aberration-free 3D imaging with a multi-spectral matrix microscope
      Victor Barolle
    • Wavefront shaping and Optical Memory Effect of ex-vivo cataractous crystalline lenses
      Alba Panigua Diaz
    • On imaging of structure and function of the human cornea
    • Eye in Focus: Strategies for Extending the Imaging Depth of Vitreous with SS-OCT
      Vasantha Kumar Kathirvelu
  • 8:30

    Parallel session II.2 – Novel methods of eye imaging

    Chaired by Chris Dainty, Auditorium B
    • Invited: Full field optical coherence tomography: in vivo and in vitro ocular imaging
    • Diffused-illumination full-field swept-source optical coherence tomography
      Leo Puyo
    • Melanin-specific contrast retinal imaging of small animals with polarization-diversity optical coherence tomography
      YuJie Hu
    • Invited: Spatio-temporal optical coherence tomo- graphy (STOC-T) for in vivo retinal and corneal imaging
    • In vivo imaging of retina regeneration in adult ze- brafish using ultrahigh resolution optical coherence tomography
      Juliane Hammer
  • 10:20

    Coffee break

  • 10:50

    Parallel session III.1 – Molecular processes of vision

    • Invited: A structure network-based computational model for screening rhodopsin mutants and pharmacological chaperones
    • Invited: Development of fluorinated derivatives of retinal analog: emixustat as drug candidates for the treatment of retinal degenerative diseases
    • Invited: Recombinant protein delivery for the treatment of inherited retinal diseases
    • Invited:Structural mechanisms and drug-receptor interactions leading to biased signaling of G protein coupled receptors
    • From Structure to Diagnosis: Unveiling Protein Conformational Changes to Drive Innovations in Ophthalmic Research
  • 10:50

    Parallel session III.2 – Functional and contrast enhancement in retinal imaging

    • Invited: Optoretinography – technology, mechanisms and applications
    • Invited: Real-time, high-throughput digital hologram rendering for Doppler imaging and optical coherence tomography in ophthalmology. Estimation of blood volume rate and resistivity changes in retinal arteries.
    • Invited: Progress on assessment of retinal physiology with optoretinography (ORG)
    • Invited: Light-evoked retinal pigment epithelium dynamics revealed by optoretinography
    • Optoretinography: measuring objective functional responses to light in human and mouse eyes
  • 12:40

    Lunch break

  • 13:40

    Planary: The three laws of communication

    Jean-Iuc Doumont
  • 14:40

    Industrial highlights

    • Collaborative Progress in Ophthalmology: Heidelberg Engineering's Research and Innovation
    • Eye as a window to the brain: applications in ophthalmology and beyond
    • From Research to Impact: The ZEISS Approach to Open Innovation
  • 15:40

    Coffee break

  • 16:10

    Plenary: Precise genome editing in the eye: curing blindness is now within sight

    Krzysztof Palczewski
  • 16:50

    Conference wrap-up